Entzündlicher myofibroblastischer Tumor (sog. inflammatorischer Pseudotumor) des hepatobiliären Systems

Zusammenfassung

Im vorliegenden Fallbericht wird das sonographische Bild eines diffus entlang der Gallenwege wachsenden hepatischen inflammatorischen myofibroblastischen Tumors (IMT) beschrieben. Hierbei handelte es sich um einen Zufallsbefund, der sich sonographisch als periportale echoarme infiltrierend wachsende Raumforderung darstellte. Da bei diesem Bild insbesondere maligne Prozesse differenzialdiagnostisch abgegrenzt werden müssen, sollte wie im vorliegenden Beispiel eine histologische Befundsicherung angestrebt werden.

Abstract

The purpose of this report is to describe the ultrasonographic features of hepatic inflammatory myofibroblastic tumour (IMT). This tumour presented as an area of periportal soft-tissue infiltration. Because periportal infiltration is a common feature in both IMT and other malignant tumours of the hepatic portal, histological examination should be considered before final diagnosis and treatment.

Gallenwege - intrahepatische Pathologie - Differentialdiagnose, Leber, Pathologie - Leber Neoplasien, Pathologie - Sonographie - Magnetresonanztomographie

Bile ducts - intrahepatic pathology - diagnosis, differential, liver pathology - liver neoplasms, pathology - ultrasonography - magnetic resonance imaging

Literatur

• 1 Coffin C M, Watterson J, Priest J R. et al . Extrapulmonary Inflammatory Myofibroblastic Tumor (Inflammatory Pseudotumor). a Clinicopathologic and Immunohistochemical Study of 84 Cases.  Am J Surg Pathol. 1995;  19 859-872
• 2 Krech R H, Erhardt-Domagalski M, Neumann H. Inflammatory Pseudotumor of the Liver. Morphologic and Cytophotometry Studies and Differential Diagnosis.  Pathologe. 1995;  16 415-420
• 3 Coffin C M, Humphrey P A, Dehner L P. Extrapulmonary Inflammatory Myofibroblastic Tumor: a Clinical and Pathological Survey.  Semin Diagn Pathol. 1998;  15 85-101
• 4 Philips E W. Intrathoracic Xanthomatous New Growth: Report of Two Cases and Collection of 3 Similar Cases in the Literature.  J Thorac Surg. 1937;  87 74-95
• 5 Pack G T, Baker H W. Total Right Lobectomy: Report of One Case.  Ann Surg. 1953;  138 253-258
• 6 Horiuchi R, Uchida T, Kojima T. et al . Inflammatory Pseudotumor of the Liver. Clinicopathologic Study and Review of the Literature.  Cancer. 1990;  65 1583-1590
• 7 Kelekis N L, Warshauer D M, Semelka R C. et al . Inflammatory Pseudotumor of the Liver: Appearance on Contrast Enhanced Helical Ct and Dynamic Mr Images.  J Magn Reson Imaging. 1995;  5 551-553
• 8 Isobe H, Nishi Y, Fukutomi T. et al . Inflammatory Pseudotumor of the Liver Associated With Acute Myelomonocytic Leukemia.  Am J Gastroenterol. 1991;  86 238-240
• 9 Shek T W, Ng I O, Chan K W. Inflammatory Pseudotumor of the Liver. Report of Four Cases and Review of the Literature.  Am J Surg Pathol. 1993;  17 231-238
• 10 Lee S L, DuBois J J. Hepatic Inflammatory Pseudotumor: Case Report, Review of the Literature, and a Proposal for Morphologic Classification.  Pediatr Surg Int. 2001;  17 555-559
• 11 Venkataraman S, Semelka R C, Braga L. et al . Inflammatory Myofibroblastic Tumor of the Hepatobiliary System: Report of Mr Imaging Appearance in Four Patients.  Radiology. 2003;  227 758-763
• 12 Abehsera M, Vilgrain V, Belghiti J. et al . Inflammatory Pseudotumor of the Liver: Radiologic-Pathologic Correlation.  J Comput Assist Tomogr. 1995;  19 80-83
• 13 Flisak M E, Budris D M, Olson M C. et al . Inflammatory Pseudotumor of the Liver: Appearance on Mri.  Clin Imaging. 1994;  18 1-3
• 14 Tai Y S, Lin P W, Chen S G. et al . Inflammatory Pseudotumor of the Liver in a Patient With Human Immunodeficiency Virus Infection.  Hepatogastroenterology. 1998;  45 1760-1763
• 15 Kim S R, Hayashi Y, Kudo M. et al . Inflammatory Pseudotumor of the Liver in a Patient With Chronic Hepatitis C: Difficulty in Differentiating it From Hepatocellular Carcinoma.  Pathol Int. 1999;  49 726-730
• 16 Noi I, Loberant N, Cohen I. Inflammatory Pseudotumor of the Liver.  Clin Imaging. 1994;  18 283-285
• 17 Cadranel J F, Buffet C, Cauquil P. et al . Pseudotumor Nodules of the Liver in Cirrhotic Patients. Study of 7 Cases.  Gastroenterol Clin Biol. 1988;  12 833-840
• 18 Di V G, Soresi M, Patti R. et al . Concomitant Inflammatory Pseudotumor of the Liver and Spleen.  Liver. 2001;  21 217-222
• 19 Sakai M, Ikeda H, Suzuki N. et al . Inflammatory Pseudotumor of the Liver: Case Report and Review of the Literature.  J Pediatr Surg. 2001;  36 663-666
• 20 Someren A. „Inflammatory Pseudotumor” of Liver With Occlusive Phlebitis: Report of a Case in a Child and Review of the Literature.  Am J Clin Pathol. 1978;  69 176-181